October 19, 2025 at 11:05 am

H.pylori and antibiotics

What are the pros and cons of using antibiotics treatment for h pylori?

I understand using them would wipe out all the beneficial bacteria as well. And there is a chance if we don’t support the root cause of why h pylori was there in the first place there’s a chance it might come back (betaine HCl supplements to keep stomach acid level optimum? )

What if we support the gut during the antibiotics treatment with mastic gum , probiotics and gut healing supplements like bone broth, L glutamine and zinc carnosine?

  • Bernadette_Abraham

    October 20, 2025 at 2:14 pm

    @Raahema – great questions.


    The most common conventional treatment for H Pylori involves a triple therapy taken for 10 days to 2 weeks. This usually involves 2 forms of antibiotics and a PPI to reduce the acid and make the antibiotics work better. This is an aggressive treatment to eradicate the infection quickly. That’s the main benefit compared to natural alternatives, and can be beneficial in situations where “speed” is needed such as in cases of cancer for example.

    The downside however, is that recurrence after antibiotics is common, likely due to proliferation of antibiotic resistant strains and upstream root causes not being addressed as you have mentioned.

    Using antibiotics may also predispose a person to other GI microbial imbalances afterward, especially given the likelihood of a highly challenged immune system under these circumstances (antibiotics tend to allow yeast/fungal and antibiotic resistance bacterial species an opportunity to grow aggressively, given suppressed competition).

    And antibiotics may also cause nausea, diarrhea, taste changes, and fatigue; these are common short-term complaints.

    Certainly this comes down to personal choice, and if you choose to go this route, then the adjunctive therapies that you’ve mentioned to help heal the gut and support the microbiome AFTER therapy are certainly wise and beneficial.

    In fact, this protocol here can help in times when antibiotics are needed.

    I personally prefer a more natural alternative since mastic gum and sulforophane (e.g. from broccoli sprouts) have been shown to eradicate H Pylori infections, often with less to no side effects. But these are longer treatment durations (4-6 weeks) and can be more financially costly as well so that’s something to keep in mind as well.

    Regardless if someone choose antibiotics or natural therapies, retesting should always be done after the treatment, and so should addressing the root cause. That’s where introducing HCL to increase stomach acid after treatment can give a person time to resolve the environment that led to an overgrowth in the first place.

    Hope this provides some additional perspectives to consider.

    • Raahema

      October 20, 2025 at 2:48 pm

      Thanks for the detailed reply. Sourcing and pricing is one of my primary concerns with the herbal supplements. While I’m able to source mastic gum, getting my hands on broccoli sprouts supplement is proving to be very difficult. Although we get fresh broccoli here I have to get the supplement from abroad and it’s getting very pricey.

Log in to reply.